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Hormones and Anxiety Regulation

Updated: Oct 18, 2023

Hormones wield significant influence over anxiety, shaping its intensity and frequency. Within the body's stress response system, a range of hormones contribute to anxiety symptoms. Here, we delve into these key hormones and their impact on anxiety.

Cortisol: As the primary stress hormone dispatched by the adrenal glands, cortisol aids the body in responding to stressors. It achieves this by elevating blood sugar levels, suppressing the immune system, and regulating metabolism. Persistent high levels of cortisol can escalate anxiety and elevate the risk of developing anxiety disorders.

Adrenaline (Epinephrine): Released during the body's "fight-or-flight" reaction to stress, adrenaline sparks physiological shifts like heightened heart rate, increased blood pressure, and heightened alertness. While crucial in perilous situations, excessive or prolonged release of adrenaline can contribute to anxiety symptoms.

Thyroid Hormones: The thyroid gland churns out hormones, including thyroxine (T4) and triiodothyronine (T3), which govern metabolism and energy levels. Imbalances, whether in the form of an overactive thyroid (hyperthyroidism) or underactive thyroid (hypothyroidism), can lead to anxiety symptoms.

Sex Hormones: Estrogen and progesterone hold sway as primary sex hormones in females, while testosterone reigns supreme in males. Fluctuations in these hormones, particularly during distinct phases of the menstrual cycle, pregnancy, or menopause, can contribute to mood shifts and heightened susceptibility to anxiety.

GABA and Serotonin: Though not technically hormones, these neurotransmitters wield considerable influence over anxiety regulation. Gamma-aminobutyric acid (GABA) serves as an inhibitory neurotransmitter, calming the brain and alleviating anxiety. Serotonin, on the other hand, influences mood regulation and can sway anxiety levels. Discrepancies or shortages in GABA or serotonin can amplify anxiety.

It's imperative to recognize that while hormones play a part in anxiety, anxiety disorders are intricate conditions influenced by an array of factors, including genetics, environment, and psychological elements. If you're grappling with anxiety symptoms, seeking guidance from a healthcare professional ensures an accurate diagnosis and appropriate treatment.


Man with low testosterone suffering from anxiety


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